Osteoarthritis (OA) is the most common chronic condition of the joints, affecting about 27 million Americans1. Osteoarthritis is most often found in older people, but can occur in younger people as well2.

Osteoarthritis occurs when there is a breakdown in the cartilage covering the ends of bones where they meet to form a joint and allow movement. As the cartilage wears away, bones become exposed and rub against each other. The deterioration of cartilage also affects the shape and makeup of the joint so that it no longer functions smoothly2.

Osteoarthritis has no single, specific cause and there are several factors involved in the disease, including heredity and lifestyle3. The hands, knees, hips and spine are the joints most commonly affected by OA2.


  1. Lawrence RC, Felson DT, Helmick CG, et al. Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part II. Arthritis Rheum. 2008;58(1):26- 35.
  2. National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS). Available at: http://www.niams.nih.gov/Health_Info/Osteoarthritis/default.asp. Accessed November 17, 2009.
  3. Felson, David T, et al. Harrison’s Principles of Internal Medicine - 17th Ed. 2008. Available at: http://onllne.statref.com/document.aspx?fxid=55&docid=2906. Accessed September 1, 2010.

Additional Resources

The following group is dedicated to the education and assistance of patients that suffer from Osteoarthritis (OA). Find out more about OA by visiting this website:


About Endo


Endo International plc is a global specialty healthcare company focused on improving patients' lives while creating value. Endo develops, manufactures, markets, and distributes quality branded pharmaceutical and generic products as well as medical devices through its operating companies: AMS, Endo Pharmaceuticals, Paladin Labs and Qualitest.  

Endo has global headquarters in Dublin, Ireland and US headquarters in Malvern, PA. 

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