Peyronie's Disease

Peyronie's (pronounced "Pay-ROH-neez") disease is the development of scar tissue, also known as Peyronie's plaque, under the skin of the penis, causing it to curve when erect. This plaque may result from injury to the penis and/or genetic factors; however, the exact cause of Peyronie's disease is unknown. In a small percentage of men, Peyronie's disease goes away on its own, but in most cases, it will remain stable or worsen1. Treatment might be needed if the curvature is severe enough that it prevents successful sexual intercourse. Men with Peyronie's disease may complain of a variety of symptoms. Penile curvature, lumps in the penis, painful erections, soft erections, and difficulty with penile penetration due to curvature are common concerns that bring men with Peyronie's disease to see their doctors1.

You are not alone:

  • Every year, it is estimated 65,000 men are diagnosed with Peyronie's disease in the United States
  • Peyronie's disease is found in men of all ages, but is most common among men 40 to 60 years old
  • Peyronie's disease is thought to be underreported for a number of reasons, including that men may be embarrassed to seek help
  • Peyronie's disease is unlikely to go away on its own, and may get worse over time
  • Erectile dysfunction (ED) can be associated with Peyronie's disease, but Peyronie's is a distinct condition

If you think that you may have Peyronie's disease, talk to your healthcare professional.


About Endo


Endo International plc is a highly focused generics and specialty branded pharmaceutical company delivering quality medicines to patients in need through excellence in development, manufacturing and commercialization. Endo has global headquarters in Dublin, Ireland, and U.S. headquarters in Malvern, PA.


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