Breakthrough Therapeutics
Focus Areas
Innovation inspired by challenges
Endo is boldly innovating in pursuit of transforming health and health system burdens.
Through our long-standing work in endocrinology, orthopedics, and urology, as well as in hospital systems and with retail generic medications, we have developed an unmatched understanding of those we serve. We will never stop learning how to make a real difference in people's lives.
Pediatric Endocrinology
The endocrine system is a collection of glands that controls many of the body’s essential functions. When they work properly, they keep the human body operating as expected. When they malfunction, one result can be central precocious puberty (CPP).
CPP is puberty that occurs much earlier than what’s considered normal. This rare disease can be incredibly disruptive to a child’s life and stressful for caregivers, plus it can lead to long-term effects if not addressed.
Endo is dedicated to meeting the needs of children and families affected by CPP. We aim to improve outcomes for children affected by early-onset puberty through our research and development efforts, collaborations with healthcare professionals, support for patient/caregiver advocacy groups (Human Growth Foundation, MAGIC Foundation) and professional societies (Pediatric Endocrinology Nursing Society, Pediatric Endocrinology Society), and caregiver resources.
Orthopedics
Orthopedic medicine focuses on the musculoskeletal system—the skeleton and all the parts that connect to it, including bones, muscles, joints, ligaments, and tendons. Orthopedic conditions can impact people’s mobility and, by extension, their quality of life. Think of common orthopedic issues like arthritis, fractures, sports injuries, and back problems.
Endo’s long-standing work in this field started with Dupuytren’s contracture, a hand condition that results in the formation of a rope-like cord that pulls fingers toward the palm and may get worse over time. An estimated 17 million Americans* have Dupuytren’s contracture,1,2 making it difficult for them to use their hands for daily activities—even simple tasks such as placing their hands in their pockets, putting on gloves, or shaking hands.
Endo continues to conduct research focused on orthopedic conditions, including Dupuytren’s contracture, and we partner with the American Society for Surgery of the Hand, the American Association for Hand Surgery, and other orthopedic organizations to support their patient advocacy and educational work. Through all these efforts, we strive to help people overcome challenges and live the lives they want.
Urology & Men’s Health
A range of conditions can affect the urinary tract system and male reproductive system. In urology, the patient experience and the patient–provider relationship are critical. Treatment and care must be personalized and tailored to a person’s unique journey, needs, and preferences.
Our commitment to men’s health has positioned us as a leader in the space. We are passionate about the health issues affecting men today, including hypogonadism, or low testosterone, and Peyronie’s disease, a buildup of fibrous scar tissue that causes a curvature deformity of the penis.
Due to the personal nature of men’s urologic health conditions like these, men may be too uncomfortable to speak up and get help. Our dedication to these patients drives research and development endeavors, educational initiatives, and patient support. Endo is a long-time supporter and partner of medical and scientific organizations, such as the Sexual Medicine Society of North America, the American Urological Association, UroGPO, the Large Urology Group Practice Association, and the Society of Urologic Nurses and Associates, and we collaborate with urologists and advanced practice providers to understand their needs and their patients.
Sterile Injectables
We partner with hospitals and healthcare systems to reduce complexity through life-enhancing solutions, innovating together to add value where it matters—from manufacturing to treatment—so that healthcare providers can focus on patient care.
Our aseptic product portfolio spans various therapeutic categories and includes both branded and generic injectables.
Our ready-to-administer (RTA) and ready-to-use (RTU) products, available through our TruDelivery® platform, streamline hospital operations by eliminating the need for preparation time or transfer before patient administration. This can reduce preparation time, enhance convenience and workflow, and minimize potential preparation errors. All these advantages support quality care for patients in hospitals, clinics, and home health and long-term care systems.
Generics
We deliver high-quality, affordable generic medicines to patients in need through excellence in development, manufacturing, and commercialization. Drawing from over four decades of experience in the U.S. generic pharmaceutical market, we have built a well-established reputation for compliance and exceptional customer service.
We focus on therapeutically equivalent ANDA-based products, with the flexibility to explore additional offerings on a case-by-case basis. We’ve developed a track record of expertise in modified-release oral solid dosage forms, complemented by a diverse range of non-oral dosage options, including nasal sprays, inhalers, patches, and various alternative drug delivery platforms.
Canada
Paladin Pharma Inc., an Endo operating company headquartered in Montreal, Canada, specializes in acquiring in-licensing innovative pharmaceutical products for the Canadian market. Our focused marketing and sales approach has helped to elevate healthcare options across the country.
We’ve earned a reputation as a reliable and trusted specialty pharmaceutical leader, thanks to our patient-centric product development, solution-oriented business partnerships, and novel commercialization strategies.
* Dupuytren's Contracture prevalence estimation calculation: Average Dupuytren's contracture prevalence in the US (5%) multiplied by US population (332 million per 2021 US Census data)=~17 million.
References
1. How common is Dupuytren disease? Dupuytren Research, Group. April 1, 2017. Accessed: April 16, 2024. https://dupuytrens.org/faq/
2. US and world population clock. US Census Bureau. Updated April 13, 2023. Accessed April 13, 2023. https://www.census.gov/popclock/